Detailed Conference Programme

The conference will be held in three different room, which are:

  • BALO SALONU, located on the first floor (i.e., Floor M),
  • NAMIK SEVIK, located on the fourth floor (i.e., Floor P), and
  • ACELYA, located on the fourth floor (i.e., Floor P)

The ACELYA room will be open early in the morning on the first day of the conference during the pre-conference course session.

Please note that concurrent presentations in parallel sessions are indicated in different colors. The presenter of each study is given in bold font.

  • > Day 1: May 8, Monday
    Time Presentation Room
    09:00 - 10:30

    COURSE I

    Introduction to explainable machine learning with examples in healthcare

    Przemyslaw Biecek

    BALO SALONU

    COURSE II

    Removing unwanted variation from large-scale RNA sequencing data with PRPS

    Ramyar Molania and Marie Trussart

    NAMIK SEVIK

    COURSE III

    How to use cloud technologies for reliable and responsible Data Science projects?

    Erdal Coşgun, Vincent Carey, and Deniz İlhan Topçu

    ACELYA
    10:30 - 11:00

    Coffee Break

    11:00 - 12:30

    COURSE I

    Introduction to explainable machine learning with examples in healthcare

    Przemyslaw Biecek

    BALO SALONU

    COURSE II

    Removing unwanted variation from large-scale RNA sequencing data with PRPS

    Ramyar Molania and Marie Trussart

    NAMIK SEVIK

    COURSE III

    How to use cloud technologies for reliable and responsible Data Science projects?

    Erdal Coşgun, Vincent Carey, and Deniz İlhan Topçu

    ACELYA
    12:30 - 13:30

    LUNCH

    13:30 - 15:00

    HONORARY MINI SYMPOSIUM: SESSION I

    Chair: Yoav Benjamini

    > Sparse kernel factor analysis model for high-dimensional undersampled cancer data sets and supervised classification with information complexity criterion

    Hamparsum Bozdoğan

    BALO SALONU

    > Variational multiple imputation in high-dimensional regression models with missing response

    Recai M. Yücel

    BALO SALONU

    > GENESELECTML: A comprehensive way of gene selection for RNA‑seq data via machine-learning algorithms

    Özlem İlk

    BALO SALONU

    COURSE II

    Removing unwanted variation from large-scale RNA sequencing data with PRPS

    Ramyar Molania and Marie Trussart

    NAMIK SEVIK
    15:00 - 15:30

    Coffee Break

    15:30 - 17:30

    HONORARY MINI SYMPOSIUM: SESSION II

    Chair: Atilla Halil Elhan

    > Confidence intervals for the Weitzman overlapping coefficient: the Binormal approach and alternatives

    Benjamin Reiser

    BALO SALONU

    > Mapping the disease prevalence of TÜRKİYE

    Mehmet Koçak

    BALO SALONU

    > The applied statistical (data) scientist in a high-profile and societal environment - IBS and EMR

    Geert Molenberghs

    BALO SALONU

    > Ergun Karaağaoğlu & Turkish Journal of Biochemistry

    Yahya Laleli

    BALO SALONU

    COURSE II

    Removing unwanted variation from large-scale RNA sequencing data with PRPS

    Ramyar Molania and Marie Trussart

    NAMIK SEVIK
    17:30 - 18:30

    HONORARY MINI SYMPOSIUM: SESSION III

    Chairs: İlker Ünal and Erdal Çoşgun

    H. Refik Burgut and A. Ergun Karaağaoğlu

    BALO SALONU
    18:30 - 20:30

    Opening Cocktail (at Saint Voukolos Church) (How to Reach?: https://tinyurl.com/2bxrhfu3)


  • > Day 2: May 9, Tuesday
    Time Presentation Room
    08:00 - 08:30

    Registration Opens

    08:30 - 09:30

    WELCOME SESSION

    > Talk by EMR 2023 Conference Chair (Assoc. Prof. Dr. Gökmen Zararsız)

    > Talk by EMR-IBS President (Prof. Dr. Konstantinos Fokianos)

    > Talk by TÜBİTAK President (Prof. Dr. Hasan Mandal)

    > Recital of Turkish Music

    BALO SALONU
    09:30 - 10:15

    KEYNOTE LECTURE

    Chair: Karen Kafadar

    BIOCONDUCTOR: Evolving an open source ecosystem for genomic data science

    Vincent Carey

    BALO SALONU
    10:15 - 10:30

    Short Coffee Break

    10:30 - 12:00

    INVITED SESSION 1: FUNCTIONAL DATA ANALYSIS

    Chair: Philip T. Reiss

    > Functional data analyses to account for and interpret glucose patterns in continuous glucose monitoring

    Emrah Gecili and Rhonda Szczesniak

    BALO SALONU

    > Incorporating shared peptides for improved inference on the proteins' abundance based on mass spectrometry data

    Malgorzata Bogdan

    BALO SALONU

    > Functional additive models for shapes and forms of plane curves

    Almond Stöcker, Lisa Steyer, and Sonja Greven

    BALO SALONU

    CONTRIBUTED SESSION 1: MULTIVARIATE STATISTICS

    Co-Chairs: Daniel Yekutieli and Özlem İlk Dağ

    > Estimation of average causal effect in clustered data with covariate measurement error

    Recai̇ M. Yücel, Raina E. Josberger, and Meng Wu

    NAMIK SEVIK

    > The chernoff faces method for visualizing complex data: An application for identifying differences between Covid-19 and control groups

    Elif Kaymaz, Ferhan Elmalı, Büşra Emir, Fatma Ezgi Can, and Mustafa Agah Tekindal

    NAMIK SEVIK

    > Viral load dynamics of Sars-Cov-2 delta and omicron variants following multiple vaccine doses and previous infection

    Naama M. Kopelman, Yonatan Woodbridge, Sharon Amit, and Amit Huppert

    NAMIK SEVIK

    > Evaluating univariate, multivariate reference interval methods: A comparative analysis

    Esra Kutsal Mergen and Sevilay Karahan

    NAMIK SEVIK

    > Evaluation of objective structured examination tool with classical testing institution, generalizability theory and item response theory

    M. Yasemin Akşehirli Seyfeli, Atilla Halil Elhan, Zeynep Baykan, Gözde E. Zararsız, Orhun Öztürk, Gökmen Zararsız, and Ahmet Öztürk

    NAMIK SEVIK
    12:00 - 12:15

    Short Coffee Break

    12:15 - 13:00

    PLENARY LECTURE

    Chair: H. Refik Burgut

    Replicability issues in medical research: Science and politics

    Yoav Benjamini

    BALO SALONU
    13:00 - 14:00

    Lunch

    14:00 - 14:45

    MARVIN ZELEN MEMORIAL LECTURE

    Chair: Urania Dafni

    Dynamic evaluation of Covid-19 clinical states by means of multi state models

    Guadalupe Gómez Melis

    BALO SALONU
    14:45 - 16:15

    INVITED SESSION 2: BIOINFORMATICS AND HIGH DIMENSIONAL DATA ANALYSIS

    Chair: Vincent Carey

    > Removi̇ng unwanted variation from large gene expression data with RUV-III-PRPS

    Ramyar Molania

    BALO SALONU

    > Validation of model selection procedures in high-dimensional analysis

    Victor Kipnis, Grant Izmirlian, and Douglas Midthune

    BALO SALONU

    > Rapidly advancing CRISPR systems hold a great potential in research on drug targets

    Göknur Giner

    BALO SALONU

    YOUNG STATISTICIAN SHOWCASE

    Chair: Dimitris Karlis

    > Modified SHAP method for seasonal vaccination status

    Bekir Çetintav, Selim Çetin, and Ahmet Yalçın

    NAMIK SEVIK

    > SimElegans: A Shiny app for GO analysis

    İrem Kahveci, H. Furkan Kepenek, and Dinçer Göksülük

    NAMIK SEVIK

    > Real-time detection of the start and subsequent epidemic states of HIV outbreaks

    Valia Baralou, Argiro Karakosta, Christos Thomadakis, Nikos Demiris, Nikos Pantazis, Olga Anagnostou, Christos Danopoulos, Dimitris Katsiris, and Giota Touloumi

    NAMIK SEVIK

    > Model based clustering for spatial data

    Anna Nalpantidi

    NAMIK SEVIK

    > Multilevel Bayesian network to model child morbidity using Gibbs sampling

    Bezalem Eshetu Yirdaw and Legesse Kassa Debusho

    NAMIK SEVIK
    16:15 - 16:45

    Coffee Break

    16:45 - 17:30

    PLENARY LECTURE

    Chair: Hamparsum Bozdoğan

    Simulation approach in the design and planning cancer screening trials

    Ping Hu

    BALO SALONU
    17:30 - 18:30

    ROUND TABLE

    Co-Chairs: Geert Molenberghs and David M. Steinberg

    The role of statistical experts during the COVID-19 pandemic

    Arne Bathke, Ralph Brinks, Filomena Maggino, Bhramar Mukherjee, and Amit Huppert

    BALO SALONU

    CONTRIBUTED SESSION 2: STATISTICAL MODELING AND COMPUTATIONAL METHODS

    Co-Chairs: George Dennis Papandonatos and Ferhan Elmalı

    > Replicability across multiple studies

    Ruth Heller and Marina Bogomolov

    NAMIK SEVIK

    > Modelling longitudinal cognitive test data with ceiling effects and left skewness

    Denitsa Grigorova, Dean Palejev, and Ralitza Gueorguieva

    NAMIK SEVIK

    > Branching modelling of mutations and risk assessment in cancer research

    Maroussia Slavtchova-Bojkova and Kaloyan Vitanov

    NAMIK SEVIK

    > Joint spatiotemporal modelling of human immunodeficiency virus and tuberculosis in ethiopia using a Bayesian hierarchical approach

    Legesse Kassa Debusho and Leta Lencha Gemechu

    NAMIK SEVIK

    > Comparing frequentist and Bayesian approaches for mixed design anova in repeated measurements: a simulation study with exponential distributions

    Zeynep Özel, Ebru Kaya Başar, and Mustafa Agah Tekindal

    NAMIK SEVIK
    18:30 - 19:45

    POSTER SESSION

    BALO SALONU
    19:00 - 19:45

    EMR BUSINESS MEETING

    NAMIK SEVIK
    20:00 - 23:00

    GALA DINNER (at North Pier's İzmir) (How to Reach?: https://tinyurl.com/yckkh8s3)


  • > Day 3: May 10, Wednesday
    Time Presentation Room
    08:30 - 10:00

    INVITED SESSION 3: CLINICAL BIOSTATISTICS AND SURVIVAL ANALYSIS

    Chair: David M. Steinberg

    > Missing time-dependent covariate values in a Cox model – joint models approach versus combination of multiple imputation and joint models

    Havi Murad, Nirit Agay, and Rachel Dankner

    BALO SALONU

    > Estimating optimal individualized treatment rules with multistate processes

    Giorgos Bakoyannis

    BALO SALONU

    > Statistical inference for complex time-to-event data under non-randomized cohorts

    KyungMann Kim, Tuo Wang, Lu Mao, and Aldo Cocco

    BALO SALONU

    CONTRIBUTED SESSION 3: SURVIVAL ANALYSIS

    Co-Chairs: Guadalupe Gómez Melis and Victor Kipnis

    > Data-driven simulations for quantitative bias analyses in real-world survival analyses

    Michal Abrahamowicz, Marie-Eve Beauchamp, Anne-Laure Boulesteix, Tim Morris, Willi Sauerbrei, and Jay Kaufman

    NAMIK SEVIK

    > Conditional randomization test for average treatment effect with survival forest

    Mehmet Ali̇ Kaygusuz and Vilda Purutçuoğlu

    NAMIK SEVIK

    > Reconstructing survival data from published Kaplan-Meier curves

    Georgia Rompoti, Dimitris Karlis, and Urania Dafni

    NAMIK SEVIK

    > Methodological issues with proportional hazard models

    Maria-Tereza Dellaporta, Dimitris Karlis, and Urania Dafni

    NAMIK SEVIK
    10:00 - 10:30

    Coffee Break

    10:30 - 11:15

    PLENARY LECTURE

    Chair: Yoav Benjamini

    Accounting for overdiagnosis in estimating components of survival time in randomized cancer screening trials

    Karen Kafadar

    BALO SALONU
    11:15 - 12:45

    INVITED SESSION 4: RECENT ADVANCES IN BIOSTATISTICS

    Chair: Ruth Heller

    > Biostatistics and SARS-CoV-2: research, policy advice, and communication

    Geert Molenberghs

    BALO SALONU

    > In Silico: Simulators and emulators in the European human brain project

    David M. Steinberg, Mira Marcus-Kalish, David Refaeli, Gilad Shapira, and Ella Shaposhnik

    BALO SALONU

    > Incorporating fuzzy logic philosophy in the evaluation of forecasting models

    Çağdaş Hakan Aladağ

    BALO SALONU

    CONTRIBUTED SESSION 4: GENOMICS AND PROTEOMICS

    Co-Chairs: Ramyar Molania and Przemyslaw Biecek

    > Stacking based approaches for survival analysis of RNA-sequencing data

    Ahu Cephe, Necla Koçhan, Ahmet Sezgin, Gözde Ertürk Zararsız, Erdem Karabulut, and Gökmen Zararsız

    NAMIK SEVIK

    > Robust protein co-expression network for Covid-19

    Ayça Ölmez and Aylin Alın

    NAMIK SEVIK

    > Infoget4gene: A user-friendly web app for genetic data analysis using R shiny

    Hamdi Furkan Kepenek, İrem Kahveci, and Dinçer Göksülük

    NAMIK SEVIK

    > Parametric bootstrap based simulation on identification of differentially expressed genes: Which one of boruta or elastic net performs better?

    Merve Kaşıkçı, Özgür Saman, and Osman Dağ

    NAMIK SEVIK

    > Determination of intron retention in gastric cancer RNA-sequence data by IRFinder-S bioinformatics algorithm

    Esma Gamze Aksel, Vahap Eldem, Selim Can Kuralay, and Gökmen Zararsız

    NAMIK SEVIK
    13:00 - 18:00

    SOCIAL PROGRAM (Ephesus & Mary's House & Sirince Village)

    18:00 - 21:00

    SOCIAL PROGRAM DINNER (at Lucien Arkas Vineyards)


  • > Day 4: May 11, Thursday
    Time Presentation Room
    08:30 - 10:00

    CONTRIBUTED SESSION 5A: MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE - I

    Co-Chairs: Aris Perperoglou and Mustafa Çavuş

    > Feature extraction and biomarker analysis for differentiating colon polyps from colonoscopic images

    Refika Sultan Doğan, Ebru Aker, Serkan Doğan, and Bülent Yılmaz

    BALO SALONU

    > WRSmoonRF: Weighted robust sufficient M-out-of-N regression forest

    Aylin Alın

    BALO SALONU

    > Optimizing number of hidden layer and hyper-parameters of deep neural network by Bayesian optimization

    Yasin Görmez, Duygu Korkmaz Yalçın, and Sıddık Keskin

    BALO SALONU

    > Automated machine learning approach in clinical settings: Predicting the future risks

    Didem Turgut, Deniz İlhan Topçu, Samet Şenel, and Cüneyt Özden

    BALO SALONU

    > A comprehensive comparison of low density lipoprotein cholesterol equations

    Serra İlayda Yerlitaş, Gözde Ertürk Zararsız, Halef Okan Doğan, Serkan Bolat, Necla Koçhan, Ahu Cephe, Gökmen Zararsız, and Arrigo F.G. Cicero

    BALO SALONU

    CONTRIBUTED SESSION 5B: CLUSTERING AND CLASSIFICATION

    Co-Chairs: Malgorzarta Bogdan and Osman Dağ

    > Bioinformatics and biostatistical models for analysis and prognosis of antimicrobial resistance

    Maya Zhelyazkova, Stefan Tsonev and Dimitar Vassilev

    NAMIK SEVIK

    > Deep neural networks for average treatment effect on biological networks

    Mehmet Ali Kaygusuz and Vilda Purutçuoğlu

    NAMIK SEVIK

    > Simultaneous scoring of clusters in recursive cluster elimination, applied on transcriptomic data analysis

    Nurten Bulut, Burcu Bakır-Güngör, Bahjat F. Qaqish, and Malik Yousef

    NAMIK SEVIK

    > The G-S-M, grouping, scoring and modeling approach. Application of biological domain knowledge for groups selection on gene expression data

    Malik Yousef and Burcu Bakır-Güngör

    NAMIK SEVIK

    > The effect of missing data imputation methods on classification performance according to different missing rates in high dimensional data

    Buğra Varol, İmran Kurt Ömürlü, and Mevlüt Türe

    NAMIK SEVIK
    10:00 - 10:30

    Coffee Break

    10:30 - 11:15

    PLENARY LECTURE

    Chair: KyungMann Kim

    20 years of statistical bioinformatics: a brief history of the limma and edgeR packages

    Gordon Smyth

    BALO SALONU
    11:15 - 12:45

    INVITED SESSION 5: BRAIN IMAGING METHODS

    Chair: R. Todd Ogden

    > Nonparametric functional data modeling of pharmacokinetic processes with applications in dynamic pet imaging

    R. Todd Ogden

    BALO SALONU

    > Investigating directional causality in multichannel brain signals: Threshold autoregressive modeling based approach

    Sipan Aslan and Hernando Ombao

    BALO SALONU

    > How reliable is resting-state functional connectivity?

    Xu Meng, Philip T. Reiss, and Ivor Cribben

    BALO SALONU

    CONTRIBUTED SESSION 6: MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE - II

    Co-Chairs: Gökmen Zararsız and Necla Koçhan

    > Health space model using deep learning

    Taesung Park and Chanhee Lee

    NAMIK SEVIK

    > How to explain carbohydrate metabolism disorders using machine learning models?

    Deniz İlhan Topçu and Banu İşbilen Başok

    NAMIK SEVIK

    > Abnormality detection and classification on mammography images via convolutional neural networks

    Hanife Avcı, Gamze Durhan, Figen Demirkazık, Meltem Gülsün Akpınar, and Jale Karakaya

    NAMIK SEVIK

    > Estimating the cost of Covid-19 to Turkish tourism with time series and machine learning models

    Günal Bilek

    NAMIK SEVIK

    > Assessing prediction accuracy of joint models: A novel approach based on mutual information criterion

    Merve Başol Göksülük, Dinçer Göksülük, and A. Ergun Karaağaoglu

    NAMIK SEVIK
    12:45 - 13:45

    Lunch

    13:45 - 14:30

    PLENARY LECTURE

    Chair: A. Ergun Karaağaoğlu

    Towards reliable empirical evidence in methodological biostatistical research: recent developments and remaining challenges

    Anne-Laure Boulesteix

    BALO SALONU
    14:30 - 16:15

    INVITED SESSION 6: MACHINE-LEARNING AND COMPUTER SCIENCE

    Chair: Taesung Park

    > Enhancing clinical trial power through covariate adjustment models: An investigation of methods, claims and realistic expectations

    Aris Perperoglou

    BALO SALONU

    > Cardiac classification using machine learning models with information complexity

    Hamparsum Bozdoğan

    BALO SALONU

    > Bringing group sparsity to Bayesian hierarchical models: Multivariate Bernoulli distribution is here to help

    Zeynep Bal, Gülay Başarır, and Mehmet Gönen

    BALO SALONU
    13:45 - 16:15

    CONTRIBUTED SESSION 7: CLINICAL TRIALS AND DIAGNOSTIC TESTS

    Co-Chairs: Aylin Alın and Sevilay Karahan

    > Practical considerations for statistical models and their implementations of phase I dose-escalation oncology trials

    Burak Kürsad Günhan, Pavel Mozgunov, and Anja Victor

    NAMIK SEVIK

    > A review on randomized controlled trials in emergency medicine: Methodological issues

    Demet Arı, Pınar Günel, Buket İpek Berk, İhsan Berk, and Vildan Sümbüloğlu

    NAMIK SEVIK

    > Nonparametric estimation of distribution function using ranked set sampling with unequal probabilities

    Yusuf Can Sevil and Tuğba Özkal Yıldız

    NAMIK SEVIK

    > Public health-focused use of Covid-19 rapid antigen PCR tests

    Yonatan Woodbridge, Yair Goldberg, Sharon Amit, Naama M. Kopelman, Micha Mandel, and Amit Huppert

    NAMIK SEVIK

    > Diabetic retinopathy diagnosis and classification

    Berk Pişkin, Aylin Alın, Rim Khazhin, Ahmet Mert Saygu, and Ahmet Ömer Özgür

    NAMIK SEVIK

    > A new estimator for the discrimination accuracy in a four-class classification problem

    Elena Nardi

    NAMIK SEVIK
    16:15 - 16:30

    Coffee Break

    16:30 - 17:30

    CLOSING REMARKS & AWARD CEREMONY


  • > Poster Session (Day 2, at BALO SALONU)
    ID Title
    PP1

    Fast and approximate inference of multilevel threshold autoregressive model for intensive longitudinal data via mean field variational bayes

    Azizur Rahman and Depeng Jiang

    PP2

    Artificial intelligence-based morphology analysis system for brain organoids

    Elifsu Polatlı, Burak Kahveci, and Sinan Güven

    PP3

    Transcriptomic profiling of induced pluripotent stem cell derived lacrimal organoids

    Burak Kahveci, Gamze Koçak, Canan Aslı Utine, Adil Mardinoğlu, Gökhan Karakülah, and Sinan Güven

    PP4

    Predicta: quick and accurate triage tool

    Vahide Gül Türkmen and Burak Kahveci

    PP5

    Modified clinical kernel using a Cox model

    Seungyeoun Lee, Inyoung Kim, and Hyunjae Lee

    PP6

    Net benefit in clinical decision making process

    Duygu Korkmaz Yalçın and İlker Ünal

    PP7

    Estimation of low-density lipoprotein cholesterol using machine learning models

    Necla Koçhan

    PP8

    Evaluation of survival tree random survival forest and Cox proportional hazard models

    Duygu Korkmaz Yalçın and Sıddık Keskin

    PP9

    Alzheimer disease classification with machine learning method

    Fatma Gül Gezer, Berfu Parçalı, Kevser Setenay Öner, and Fezan Mutlu

    PP10

    A comprehensive R Shiny web tool that combines two continuous diagnostic tests

    Serra İlayda Yerlitaş, Serra Bersan Gengeç, Gözde Ertürk Zararsız, Selçuk Korkmaz, and Gökmen Zararsız

    PP11

    A circular heatmap visualization approach for interlaboratory comparisons in ring studies

    Gözde Ertürk Zararsiz, Alexander Cecil, Jutta Lintelmann, Gernot Poschet, Jennifer Kirwan, Sven Schuchardt, Xue Li Guan, Daisuke Saigusa, David Wishart, Jiamin Zheng, Rupasri Mandal, Lisa St. John-Williams, Kendra Adams, J. Will Thompson, Michael P. Snyder, Kevin Contrepois, Songlie Chen, Nadia Ashrafi, Sumeyya Akyol, Ali Yilmaz, Stewart Graham, Thomas M. O’Connell, Karl Kalecký, Teodoro Bottiglieri, Tuan Hai Pham, Therese Koal, Jerzy Adamski, and Gabi Kastenmüller

    PP12

    A meta-analysis study for diagnosing skin cancer with machine learning techniques

    Gözde Ertürk Zararsız, Elif Çelik Gürbulak, Serra İlayda Yerlitaş, Selen Yılmaz Işıkhan, Abdullah Demirbaş, İrem Eroğlu, Aleyna Erakçaoğlu, Ragıp Ertaş, Ömer Faruk Elmas, and Gökmen Zararsız

    PP13

    Establishing continuous reference intervals for thyroid function tests

    Funda İpekten, Gözde Ertürk Zararsız, Halef Okan Doğan, Çiğdem Karakükçü, and Gökmen Zararsız

    PP14

    Review: access ccontrol in electronic medical records (EMR)

    Hilah Alnafisah, Rawaby Alsaaid, and Fatimah M. Alturkistani

    PP15

    On Performances of Different Correlation Coefficients

    Yeşim Uğur Uzun and Mehmet Mendeş